全文获取类型
收费全文 | 132141篇 |
免费 | 11322篇 |
国内免费 | 17999篇 |
专业分类
化学 | 89309篇 |
晶体学 | 3432篇 |
力学 | 4846篇 |
综合类 | 1320篇 |
数学 | 24607篇 |
物理学 | 37948篇 |
出版年
2023年 | 1126篇 |
2022年 | 1802篇 |
2021年 | 3319篇 |
2020年 | 3509篇 |
2019年 | 3548篇 |
2018年 | 2947篇 |
2017年 | 3568篇 |
2016年 | 4412篇 |
2015年 | 4290篇 |
2014年 | 5630篇 |
2013年 | 10085篇 |
2012年 | 7688篇 |
2011年 | 8345篇 |
2010年 | 7156篇 |
2009年 | 8588篇 |
2008年 | 9048篇 |
2007年 | 9391篇 |
2006年 | 8268篇 |
2005年 | 7012篇 |
2004年 | 6484篇 |
2003年 | 5687篇 |
2002年 | 4738篇 |
2001年 | 3669篇 |
2000年 | 3317篇 |
1999年 | 2787篇 |
1998年 | 2580篇 |
1997年 | 2291篇 |
1996年 | 2306篇 |
1995年 | 2179篇 |
1994年 | 1975篇 |
1993年 | 1679篇 |
1992年 | 1728篇 |
1991年 | 1152篇 |
1990年 | 918篇 |
1989年 | 827篇 |
1988年 | 743篇 |
1987年 | 570篇 |
1986年 | 489篇 |
1985年 | 633篇 |
1984年 | 504篇 |
1983年 | 266篇 |
1982年 | 456篇 |
1981年 | 657篇 |
1980年 | 591篇 |
1979年 | 574篇 |
1978年 | 484篇 |
1977年 | 378篇 |
1976年 | 327篇 |
1974年 | 130篇 |
1973年 | 206篇 |
排序方式: 共有10000条查询结果,搜索用时 187 毫秒
61.
A polystyrene-supported phosphine oxide-catalysed Beckmann rearrangement of ketoximes in 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP) has been developed. Good substrate compatibility, mild reaction conditions, good yields as well as the reusability of the catalyst/solvent made this procedure more environmentally benign. 相似文献
62.
63.
64.
Given two graphs and , a graph is -free if it contains no induced subgraph isomorphic to or . Let and be the path on vertices and the cycle on vertices, respectively. In this paper we show that for any -free graph it holds that , where and are the chromatic number and clique number of , respectively. Our bound is attained by several graphs, for instance, the 5-cycle, the Petersen graph, the Petersen graph with an additional universal vertex, and all -critical -free graphs other than (see Hell and Huang [Discrete Appl. Math. 216 (2017), pp. 211–232]). The new result unifies previously known results on the existence of linear -binding functions for several graph classes. Our proof is based on a novel structure theorem on -free graphs that do not contain clique cutsets. Using this structure theorem we also design a polynomial time -approximation algorithm for coloring -free graphs. Our algorithm computes a coloring with colors for any -free graph in time. 相似文献
65.
Diabetes mellitus (DM) is the fastest growing metabolic disorder in the world. Recently, more attention is paid to the study of natural products due to side effects of synthetic drugs. Stevia rebaudiana (Bertoni) is considered an encouraging starting point for the antidiabetic lead development. In the present study, the in vitro α-amylase inhibitory activity of the extracts of S. rebaudiana is investigated. In order to understand the molecular mechanism and future pharmacophore development, in silico study of secondary metabolites isolated from S. rebaudiana was carried out. Results indicated that water extract shows highest α-amylase inhibitory activity as compared to other extracts. Moreover, compound 20 (rebaudioside A) which has been previously reported and isolated from water extract showed the impressive binding profile with α-amylase. Therefore, our study suggests that S. rebaudiana could be used in the development of therapeutic drugs for the treatment of diabetes. 相似文献
66.
The electrochemical behavior of austenitic stainless steel (Type 304) in 3 M sulfuric acid with 3.5% recrystallized sodium chloride at specific concentrations of butan-1-ol was investigated with the aid of potentiodynamic polarization, open circuit measurement and weight loss technique. Butan-1-ol effectively inhibited the steel corrosion with a maximum inhibition efficiency of 78.7% from weight-loss analysis and 80.9% from potentiodynamic polarization test at highest concentration studied. Adsorption of the compound obeyed the Freundlich isotherm. Thermodynamic calculations reveal physiochemical interactions and spontaneous adsorption mechanism. Surface characterizations showed the absence of corrosion products and topographic modifications of the steel. Statistical analysis depicts the overwhelming influence and statistical significance of inhibitor concentration on the inhibition performance. 相似文献
67.
Tiago Augusto Donegatti Alnilan Lobato Luís Moreira Gonalves Elisabete Alves Pereira 《Electrophoresis》2019,40(22):2929-2935
Aldehydes are important compounds in a large number of samples, especially food and beverages. In this work, for the first time, cyclohexane‐1,3‐dione (CHD) was used as a derivatizing reagent aiming aldehyde (formaldehyde, acetaldehyde, propionaldehyde, and valeraldehyde) analysis by MEKC‐DAD. The optimized separation of the derivates was performed using a voltage program (+20 kV, 0–15 min.; +23 kV, 15–17 min.) at a temperature of 26°C, and using as the running buffer a mixture containing 100 mmol/L of sodium dodecyl sulfate and 29 mmol/L of sodium tetraborate at pH 9.2, with maximum absorbance at 260 nm. CHD was compared with two other derivatizing agents: 3‐methyl‐2‐benzothiazolinone hydrazone and phenylhydrazine‐4‐sulfonic acid. The CHD‐aldehyde derivatives were also characterized by LC‐MS. The calibration curves for all aldehydes had r2 above 0.999 and LODs ranged from 0.01 to 0.7 mg/L. The optimized methodology was applied in sugar cane brandy (cachaça) samples successfully. CHD showed to be an alternative derivatization reagent due to its stability, aqueous solubility, high selectivity and sensitivity, reduced impurities, and simple preparation steps. 相似文献
68.
Gunasekaran Balamurugan Sundarraman Balaji Rengan Ramesh Nattamai S.P. Bhuvanesh 《应用有机金属化学》2019,33(1)
A panel of six new arene Ru (II)‐NHC complexes 2a‐f , (NHC = 1,3‐diethyl‐(5,6‐dimethyl)benzimidazolin‐2‐ylidene 1a , 1,3‐dicyclohexylmethyl‐(5,6‐dimethyl)benzimidazolin‐2‐ylidene 1b and 1,3‐dibenzyl‐(5,6‐dimethyl)benzimidazolin‐2‐ylidene 1c ) were synthesized from the transmetallation reaction of Ag‐NHC with [(η6‐arene)RuCl2]2 and characterized. The ruthenium (II)‐NHC complexes 2a‐f were developed as effective catalysts for α‐alkylation of ketones and synthesis of bioactive quinoline using primary/amino alcohols as coupling partners respectively. The reactions were performed with 0.5 mol% catalyst load in 8 h under aerobic condition and the maximum yield was up to 96%. Besides, the different alkyl wingtips on NHC and arene moieties were studied to differentiate the catalytic robustness of the complexes in the transformations. 相似文献
69.
Pan Huang Dawen Xu Robert M. Reich Felix Kaiser Boping Liu Fritz E. Kühn 《Tetrahedron letters》2019,60(24):1574-1577
A first example of an Et2Zn mediated silylation of 1-aklynes is reported. A series of functional groups are tolerated in this reaction. Mechanistic studies support Zn alkynilides as intermediates in the reaction. This reaction protocol provides a practical method for the preparation of alkynylsilanes and expands the application of organometallic zinc in organic synthesis. 相似文献
70.
Swinhoeisterol A is a novel steroid with unusual 6/6/5/7 tetracyclic skeleton. The model compound with BCD rings is constructed by Friedel–Crafts acylation and an oxidative dearomatization as key steps. 相似文献